| # | Player | Team | Goals Total | Assists | Appearances | Minutes | Rating |
|---|---|---|---|---|---|---|---|
| 1 |  Son Heung-Min |  Los Angeles FC | 0 | 8 | 12 | 955 | 7.19 |
| 2 |  A. Dreyer |  San Diego | 6 | 7 | 15 | 1309 | 7.62 |
| 3 |  Evander |  FC Cincinnati | 9 | 6 | 14 | 1138 | 7.87 |
| 4 |  P. Owusu |  CF Montreal MON | 9 | 6 | 14 | 1108 | 7.22 |
| 5 |  P. Zinckernagel |  Chicago Fire CHI | 5 | 6 | 14 | 1142 | 7.48 |
| 6 |  C. Espinoza |  Nashville SC | 3 | 6 | 14 | 992 | 6.95 |
| 7 |  L. Langoni |  New England Revolution ENG | 3 | 6 | 12 | 814 | 7.05 |
| 8 |  T. Segovia |  Inter Miami | 2 | 6 | 13 | 1072 | 6.8 |
| 9 |  M. Moralez |  New York City FC | 1 | 6 | 14 | 1137 | 6.94 |
| 10 |  L. Messi | Inter Miami | 13 | 5 | 13 | 1177 | 8.68 |
| 11 |  M. Reus |  Los Angeles Galaxy ANG | 4 | 5 | 15 | 1025 | 6.86 |
| 12 |  F. Torres |  Austin | 1 | 5 | 15 | 1259 | 7.05 |
| 13 |  J. Pereyra |  Minnesota United FC MIN | 1 | 5 | 15 | 1296 | 7.33 |
| 14 |  Guilherme |  Houston Dynamo HOU | 8 | 4 | 14 | 1176 | 7.99 |
| 15 |  Pep Biel |  Charlotte | 7 | 4 | 15 | 1324 | 7.05 |
| 16 |  H. Mukhtar | Nashville SC | 6 | 4 | 14 | 1103 | 7.16 |
| 17 |  Z. Gozo |  Real Salt Lake SAL | 6 | 4 | 14 | 1253 | 7.39 |
| 18 |  S. Berhalter |  Vancouver Whitecaps | 6 | 4 | 14 | 1134 | 7.83 |
| 19 |  Gabriel Pec | Los Angeles Galaxy ANG | 5 | 4 | 14 | 1226 | 7.21 |
| 20 |  M. Arfsten |  Columbus Crew COL | 4 | 4 | 14 | 1230 | 7.06 |