Two-legged tie
Lokomotiv 1–3 Fenerbahçe agg. (1st 2–0 · 2nd 1–1)
1st leg
2nd leg
Rounds are shown widest-first (most ties on the left, then halves toward the final). Two-legged ties are merged with per-leg scores and aggregate. Each column lines up with the two feeders from the previous stage; advancing sides are highlighted when known.
Round of 32
Two-legged tie
Napoli 1–2 Villarreal agg. (1st 1–0 · 2nd 1–1)
1st leg
2nd leg
Two-legged tie
Sevilla 3–1 Molde agg. (1st 3–0 · 2nd 1–0)
1st leg
2nd leg
Two-legged tie
Saint Etienne 4–4 FC Basel 1893 agg. (1st 3–2 · 2nd 2–1)
Two-legged tie
Anderlecht 3–1 Olympiakos Piraeus agg. (1st 1–0 · 2nd 1–2)
Two-legged tie
Borussia Dortmund 3–0 FC Porto agg. (1st 2–0 · 2nd 0–1)
Two-legged tie
Tottenham 4–1 Fiorentina agg. (1st 1–1 · 2nd 3–0)
1st leg
2nd leg
Two-legged tie
Manchester United 6–3 FC Midtjylland agg. (1st 2–1 · 2nd 5–1)
Two-legged tie
Valencia 10–0 Rapid Vienna agg. (1st 6–0 · 2nd 0–4)
1st leg
2nd leg
Two-legged tie
FC Schalke 04 0–3 Shakhtar Donetsk agg. (1st 0–0 · 2nd 0–3)
Two-legged tie
FC Sion 3–4 SC Braga agg. (1st 1–2 · 2nd 2–2)
1st leg
2nd leg
Two-legged tie
Sparta Praha 4–0 FC Krasnodar agg. (1st 1–0 · 2nd 0–3)
Two-legged tie
Sporting CP 1–4 Bayer Leverkusen agg. (1st 0–1 · 2nd 3–1)
Two-legged tie
FC Augsburg 0–1 Liverpool agg. (1st 0–0 · 2nd 1–0)
1st leg
2nd leg
Two-legged tie
Galatasaray 2–4 Lazio agg. (1st 1–1 · 2nd 3–1)
1st leg
2nd leg
Two-legged tie
Athletic Club 2–1 Marseille agg. (1st 0–1 · 2nd 1–1)
Round of 16
Two-legged tie
Sevilla 3–0 FC Basel 1893 agg. (1st 0–0 · 2nd 3–0)
1st leg
2nd leg
Two-legged tie
Fenerbahçe 2–4 SC Braga agg. (1st 1–0 · 2nd 4–1)
1st leg
2nd leg
Two-legged tie
Borussia Dortmund 5–1 Tottenham agg. (1st 3–0 · 2nd 1–2)
Two-legged tie
Anderlecht 1–4 Shakhtar Donetsk agg. (1st 3–1 · 2nd 0–1)
Two-legged tie
Villarreal 2–0 Bayer Leverkusen agg. (1st 2–0 · 2nd 0–0)
Two-legged tie
Manchester United 1–3 Liverpool agg. (1st 2–0 · 2nd 1–1)
Two-legged tie
Valencia 2–2 Athletic Club agg. (1st 1–0 · 2nd 2–1)
1st leg
2nd leg
Two-legged tie
Sparta Praha 4–1 Lazio agg. (1st 1–1 · 2nd 0–3)
1st leg
2nd leg
Quarter-finals
Two-legged tie
SC Braga 1–6 Shakhtar Donetsk agg. (1st 1–2 · 2nd 4–0)
Two-legged tie
Sevilla 4–5 Athletic Club agg. (1st 1–2 · 2nd 2–4)
Two-legged tie
Borussia Dortmund 4–5 Liverpool agg. (1st 1–1 · 2nd 4–3)
Two-legged tie
Villarreal 6–3 Sparta Praha agg. (1st 2–1 · 2nd 2–4)
Semi-finals
Two-legged tie
Villarreal 1–3 Liverpool agg. (1st 1–0 · 2nd 3–0)
1st leg
2nd leg
Two-legged tie
Sevilla 5–3 Shakhtar Donetsk agg. (1st 2–2 · 2nd 3–1)