Set to return to MLS play, Lionel Messi has been dealt with a major defensive setback as Inter Miami released an injury update addressing Micael's status. Lionel Messi and Inter Miami suffered a 3-2 defeat against Club Leon in the Leagues Cup, and following their elimination from the tournament, the 2026 MLS regular season has shifted back to being their primary focus. However, the back line has taken a major hit after Inter Miami released an official injury update on center back Micael. After starting Wednesday’s match against Club Leon, Micael was forced to exit in the 33rd minute after twisting his ankle and being unable to continue. Though he managed to walk off the pitch under his own power, Fricio Caicedo came on as his replacement at center back in a match that ultimately ended in a 3-2 victory for the Mexican side, leaving Inter Miami eliminated from the Leagues Cup in the round of 16. The day after the elimination, Inter Miami released a statement addressing Micael’s condition. “Micael underwent an MRI today, which confirmed that he has a sprained right ankle sustained during last night’s Leagues Cup match against Club Leon,” part of the official update read. While confirming the injury, the Florida side did not disclose the severity or provide a firm recovery timeline. Instead, Inter Miami noted that Micael will begin a period of rest and treatment, adding that “his progress will dictate his gradual return to team training.“ Micael #16 of Inter Miami CF reacts after suffering an injury against Club Leon. (Rich Storry/Getty Images) Asked about the Brazilian’s injury during his post-match press conference, manager Guillermo Hoyos spoke candidly about what losing him would mean for the squad: “Micael has a significant sprain, and we will see what is determined during the medical examination. But it is a significant sprain, and for us, it would also be a significant loss. He is very important.“ How long will Micael be out? Much like Messi’s importance in the attack, Micael has established himself as the anchor of the defense, featuring in every single match for Inter Miami this season except for a MLS Matchday 4 clash against Charlotte FC back in March when he was rested, totalling 22 games. Now, his target return date will depend entirely on the severity of the sprain. A Grade 3 sprain, which involves a complete ligament tear and carries a two-to-three-month recovery period, seems unlikely given that Micael walked off the field unaided. If he suffered a Grade 1 sprain (micro-tears) or a Grade 2 sprain (partial tearing), his recovery timeline will likely range anywhere from one to six weeks. Who will replace Micael? Micael has cemented his status as a cornerstone of the defense while also providing a dangerous aerial threat, evidenced by his recent goal off a Messi corner kick against Atletico San Luis. Now, Hoyos faces the task of replacing a player who has arguably been Inter Miami’s most consistent defender this season. In terms of stylistic fit, recent signing Fricio Caicedo is the most natural replacement. Compared to options like Ian Fray, Gonzalo Lujan, or a returning Maximiliano Falcon, the Ecuadorian defender offers a 6-foot-4 frame and a left-footed profile that make him the ideal candidate to preserve the team’s build-up play from the left side of defense.