Two-legged tie
Orlando Pirates 1–1 Simba agg. (1st 1–0 · 2nd 1–0)
Rounds are shown widest-first (most ties on the left, then halves toward the final). Two-legged ties are merged with per-leg scores and aggregate. Each column lines up with the two feeders from the previous stage; advancing sides are highlighted when known.
Two-legged tie
Orlando Pirates 1–1 Simba agg. (1st 1–0 · 2nd 1–0)
Two-legged tie
Pyramids FC 0–2 TP Mazembe agg. (1st 0–0 · 2nd 2–0)
TP MazembePyramids FCTwo-legged tie
Renaissance Berkane 2–2 AL Masry agg. (1st 2–1 · 2nd 1–0)
Two-legged tie
Al-Ittihad 0–1 Al Ahli Tripoli agg. (1st 0–0 · 2nd 1–0)
Two-legged tie
Renaissance Berkane 4–2 TP Mazembe agg. (1st 1–0 · 2nd 4–1)
Two-legged tie
Al Ahli Tripoli 1–2 Orlando Pirates agg. (1st 0–2 · 2nd 0–1)
