Western Conference
| # | Team | P | W | D | L | GF | GA | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Vancouver Whitecaps | 14 | 10 | 2 | 2 | 34 | 12 | 22 | 32 | DDWLW |
| 2 |  San Jose Earthquakes JOS | 15 | 10 | 2 | 3 | 34 | 15 | 19 | 32 | DDLLW |
| 3 |  Real Salt Lake SAL | 14 | 8 | 2 | 4 | 26 | 19 | 7 | 26 | WLWWD |
| 4 |  FC Dallas DAL | 15 | 7 | 4 | 4 | 30 | 22 | 8 | 25 | WWLWW |
| 5 |  Los Angeles FC | 15 | 7 | 3 | 5 | 24 | 17 | 7 | 24 | DLLLW |
| 6 |  Seattle Sounders SEA | 13 | 7 | 3 | 3 | 17 | 11 | 6 | 24 | DDWLL |
| 7 |  Houston Dynamo HOU | 14 | 7 | 1 | 6 | 19 | 23 | -4 | 22 | WWLWD |
| 8 |  Minnesota United FC MIN | 15 | 6 | 4 | 5 | 18 | 22 | -4 | 22 | WDLLD |
| 9 |  Los Angeles Galaxy ANG | 15 | 5 | 5 | 5 | 22 | 22 | 0 | 20 | DWLWD |
| 10 |  San Diego | 15 | 4 | 5 | 6 | 30 | 27 | 3 | 17 | DDWDL |
| 11 |  Colorado Rapids COL | 15 | 5 | 1 | 9 | 25 | 24 | 1 | 16 | LLWLL |
| 12 |  St. Louis City | 14 | 4 | 4 | 6 | 16 | 20 | -4 | 16 | LWWDW |
| 13 |  Portland Timbers POR | 14 | 4 | 2 | 8 | 22 | 28 | -6 | 14 | LWDLL |
| 14 |  Austin | 15 | 3 | 5 | 7 | 19 | 31 | -12 | 14 | WDLLL |
| 15 |  Sporting Kansas City KAN | 14 | 3 | 2 | 9 | 14 | 36 | -22 | 11 | DLWWL |
Eastern Conference
| # | Team | P | W | D | L | GF | GA | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  Nashville SC | 14 | 10 | 3 | 1 | 31 | 11 | 20 | 33 | DDWWW |
| 2 |  Inter Miami | 15 | 9 | 4 | 2 | 39 | 28 | 11 | 31 | LWWWW |
| 3 |  Chicago Fire CHI | 14 | 8 | 2 | 4 | 27 | 16 | 11 | 26 | LLWWW |
| 4 |  New England Revolution ENG | 14 | 8 | 1 | 5 | 22 | 18 | 4 | 25 | WWLWL |
| 5 |  New York Red Bulls YOR | 15 | 6 | 4 | 5 | 25 | 32 | -7 | 22 | LWWDW |
| 6 |  Charlotte | 15 | 6 | 3 | 6 | 24 | 23 | 1 | 21 | LDLWW |
| 7 |  FC Cincinnati | 15 | 5 | 5 | 5 | 36 | 37 | -1 | 20 | WDLDW |
| 8 |  New York City FC | 15 | 5 | 4 | 6 | 25 | 21 | 4 | 19 | LWWDL |
| 9 |  DC United UNI | 15 | 4 | 6 | 5 | 21 | 25 | -4 | 18 | WDLDD |
| 10 |  Columbus Crew COL | 15 | 4 | 4 | 7 | 21 | 23 | -2 | 16 | LLLDW |
| 11 |  CF Montreal MON | 14 | 4 | 2 | 8 | 22 | 31 | -9 | 14 | LWDLD |
| 12 |  Orlando City SC | 15 | 4 | 2 | 9 | 23 | 44 | -21 | 14 | WLWDL |
| 13 |  Toronto FC TOR | 14 | 3 | 5 | 6 | 22 | 29 | -7 | 14 | LDLLL |
| 14 |  Atlanta United FC | 14 | 3 | 2 | 9 | 14 | 23 | -9 | 11 | WWLDL |
| 15 |  Philadelphia Union PHI | 15 | 1 | 4 | 10 | 18 | 30 | -12 | 7 | DLLDL |