 F. Peñaloza | In | 2024-03-22 | Free |  Comunal Cabrero |  Independiente |
 G. Mosquera | Out | 2023-03-01 | Free | Independiente |  General Velásquez |
 A. Silvestre | Out | 2023-03-01 | Free | Independiente |  Deportes Quillón |
 J. Navarro | Out | 2023-03-01 | Free | Independiente | Deportes Quillón |
 M. Godoy | Out | 2023-03-01 | Free | Independiente |  Iberia |
 J. Guzmán | Out | 2023-02-01 | Free | Independiente |  Concepción CON |
 F. Escobar | Out | 2023-02-01 | Free | Independiente |  Linares Unido |
 F. Coronel | Out | 2023-01-15 | Free | Independiente |  24 de Setiembre |
 P. Cabrera | Out | 2023-01-07 | | Independiente |  Curico Unido CUR |
 O. Aravena | Out | 2023-01-07 | | Independiente |  Union La Calera UNI |
 Á. Díaz | Out | 2023-01-07 | Free | Independiente | Linares Unido |
 Á. Garrido | Out | 2023-01-07 | N/A | Independiente |  Huachipato HUA |
 D. Vallejos | Out | 2023-01-07 | Free | Independiente | Linares Unido |
 F. Neira | In | 2022-08-01 | Loan |  Universidad de Concepcion CON | Independiente |
| Á. Garrido | In | 2022-08-01 | Loan | Huachipato HUA | Independiente |
 C. Monsalve | Out | 2022-07-01 | Free | Independiente | Linares Unido |
 S. Muñoz | Out | 2022-03-25 | Free | Independiente | Iberia |
 Christofer Eduardo Godoy Jerez | Out | 2022-03-15 | Free | Independiente | Deportes Quillón |
| O. Aravena | In | 2022-03-01 | Loan | Union La Calera UNI | Independiente |
| P. Cabrera | In | 2022-03-01 | Loan | Curico Unido CUR | Independiente |
 Benjamín Sebastián Lagos Yévenes | In | 2022-03-01 | Free | Deportes Quillón | Independiente |
 Marcelo Eduardo Téllez Soto | In | 2022-03-01 | Free | — | Independiente |
 F. Manzo | Out | 2022-02-15 | Free | Independiente | Concepción CON |
 N. Millán | Out | 2022-02-13 | Free | Independiente |  Ferro Carril Oeste LP |
 Ricardo Andrés Carcamo Vallejos | In | 2022-02-01 | Free | Concepción CON | Independiente |
 S. Julio | Out | 2022-02-01 | Free | Independiente | Iberia |
| F. Coronel | In | 2022-02-01 | Free |  Rubio NU RUB | Independiente |
 C. González | Out | 2022-02-01 | Free | Independiente |  Deportes Valdivia |
 Cegy Alfredo Duran Manque | In | 2022-02-01 | Free |  D. Puerto Montt | Independiente |
 G. Medina | Out | 2022-02-01 | N/A | Independiente |  San Marcos de Arica MAR |
 Jhon Alejandro Jorquera Ramos | Out | 2022-02-01 | Free | Independiente | Deportes Valdivia |
 Felipe Esteban Ramos Hellman | In | 2022-02-01 | Free | Deportes Quillón | Independiente |
| C. Monsalve | In | 2022-02-01 | Free |  Trasandino | Independiente |
 Ignacio Camilo Azúa Miranda | Out | 2022-02-01 | Free | Independiente | San Marcos de Arica MAR |
 Gabriel Eduardo Sandoval Alarcón | Out | 2022-02-01 | Free | Independiente | Iberia |
 C. Morales | Out | 2022-01-07 | Free | Independiente |  Deportes Rengo |
 Matías Alejandro Pinto Aránguiz | In | 2022-01-07 | Free |  Colchagua | Independiente |
| G. Mosquera | In | 2022-01-07 | Free | Concepción CON | Independiente |
 Sebastián Villalobos Campillay | In | 2022-01-07 | Free |  Deportes Vallenar | Independiente |
 M. Alegre | Out | 2022-01-07 | Free | Independiente |  Recoleta |
 Luciano Alexis Cisterna Torreblanca | In | 2022-01-07 | Free |  Colina | Independiente |
 A. Lagos | Out | 2022-01-07 | Free | Independiente | — |
 Luciano Andrés Araya Escobar | In | 2022-01-07 | Free | Colchagua | Independiente |
| Á. Díaz | In | 2022-01-07 | Free | Colchagua | Independiente |
 N. Carvajal | Out | 2022-01-07 | Free | Independiente | Recoleta |
| D. Vallejos | In | 2022-01-07 | Free |  Santiago Wanderers WAN | Independiente |
 Oskar Francisco Méndez Contreras | In | 2022-01-07 | Free | Deportes Quillón | Independiente |
 Tomás Ignacio González Rodríguez | In | 2022-01-07 | Free | Colchagua | Independiente |
 V. Ramírez | Out | 2022-01-07 | Free | Independiente |  Municipal Salamanca |
| M. Godoy | In | 2021-09-01 | Free | Huachipato HUA | Independiente |
